Cyclobenzaprine Flexeril Side Effects & Interactions

There are some alternative combinations to try rather than the cyclobenzaprine-ibuprofen mix. Just as you might have suspected, cyclobenzaprine’s muscle-relaxing effects start in the central nervous system (CNS). In this post, we’ll go over why you might want to avoid mixing the two drugs. As it happens, the cyclobenzaprine-ibuprofen mix is, more often than not, a fruitless combination. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

That said, you should still connect with your doctor before taking ibuprofen with a muscle relaxant. It’s also important to consider the dose of each medication. According to Addiction Resource, taking muscle relaxants and ibuprofen together at higher doses can lead to slowed breathing, headache, nausea, tiredness, or constipation. A 2022 study in CNS Drugs found that will flexeril fail a drug test new users of muscle relaxants who also took a precipitant drug (such as NSAIDs or antibiotics) were more likely to suffer an unintentional traumatic injury. It is crucial to consult with a healthcare professional or pharmacist before combining cyclobenzaprine and ibuprofen to assess the potential risks, consider alternative options, or adjust the dosage accordingly.

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Both of them are used for pain relief but have different mechanisms. In most cases, it is advised not to take an anti-inflammatory drug and a muscle relaxant simultaneously, as they might be contra-indicated. Three months after the ED visit, most patients had recovered, although nearly one-fourth in each study group still reported moderate or severe LBP and use of medication for LBP (Table 5). Opioid use for treating LBP was reported by 2.3% (95% CI, 0.8 to 5.3%) of participants. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.

Addiction Resource is an educational platform for sharing and disseminating information about addiction and substance abuse recovery centers. Addiction Resource is not a healthcare provider, nor does it claim to offer sound medical advice to anyone. Addiction Resource does not favor or support any specific recovery center, nor do we claim to ensure the quality, validity, or effectiveness of any particular treatment center. No one should assume the information provided on Addiction Resource as authoritative and should always defer to the advice and care provided by a medical doctor. Valerian is an herbal substance that is used to support neck and shoulder tension.

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Flexeril High: Why This Muscle Relaxer is Creating Dependency

This addiction is marked by compulsive drug-seeking behaviors, even when the negative effects of these behaviors are fully recognized. There is also the possibility of becoming psychologically dependent on Flexeril because of the feelings of relaxation. Flexeril on its own may not be as susceptible to creating addiction but when it’s abused, there’s a much greater risk. And when cyclobenzaprine and alcohol, opioids, or drugs are used in combination, that risk becomes even higher. People will abuse cyclobenzaprine to enhance the effects of alcohol or mind-altering drugs. As a result, the cyclobenzaprine high can actually end up leading to the development of addictions to other drugs as well.

  • In fact, the DEA has not officially listed cyclobenzaprine as a controlled substance at all.
  • Of the 323 deemed eligible for participation, 107 were randomized to receive placebo and 108 each to cyclobenzaprine and to oxycodone/acetaminophen.
  • According to medical doctors from the USA, these drugs are used for the treatment of anxiety disorders, insomnia, epilepsy, seizure disorders, and agitation.
  • It occurred to me that it might work even better if I used a little more than I normally would.

They can provide personalized advice based on your medical history and current medications to ensure your safety and optimize the pain management approach. Blood thinners such as anticoagulants and antiplatelets are medications used to promote proper blood flow in blood vessels. However, when used with muscle relaxants, these can increase the risk of thromboembolism and neurologic disorders. Like spasmolytic agents, benzodiazepines work by inhibiting the excitatory neurotransmitters in the brain.

Consulting a healthcare professional is crucial for proper guidance and monitoring when using Flexeril to minimize the risk of addiction. Gabapentin is an anticonvulsant medication that works by decreasing abnormal excitement in the brain. Many patients use this drug to control seizures and relieve nerve pain. When combined with muscle relaxers, this can lead to an increase in the severity of CNS side effects. Eventually, this could cause severe dizziness and drowsiness.

We assessed the actual RMDQ score at 1-week and 3-month follow-up as prespecified secondary outcomes; however, these were not described explicitly in the protocol (Supplement 1). Although it’s common to take ibuprofen for common pains, it’s important to know how it might interact with other common medications you might already be taking. Ibuprofen somewhat thins your blood, so taking blood thinners with ibuprofen can cause excessive bleeding, according to GoodRx. People might also take low-dose aspirin for their heart, but taking it with ibuprofen can lead to stomach ulcers. You should also avoid other NSAIDs if you’re taking ibuprofen.

However, in general, physicians will prescribe Flexeril dosages according to the guidelines below as provided by the Mayo Clinic. Any muscle relaxant, including the following list, should be effective in treating acute muscle pain/spasms when used at the proper dose. Although Skelaxin and Flexeril are both in the same drug category (skeletal muscle relaxants), they do have some differences, such as side effects, dose, and pricing, as outlined above.

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